Source: dels.nas.edu
Topic: Chemical Industry
Sort Desciption: Chemical Industry Perspective. fi. Toxicology and epidemiology are critical tools to. assess the potential impact of chemicals on. health and safety ...
Content Inside: 1 Chemical Industry Perspective: Current Toxicogenomics Challenges and Future Directions Richard A. Becker, Ph.D., DABT American Chemistry Council January 4, 2005 Washington, DC 2 Chemical Industry Perspective fi Toxicology and epidemiology are critical tools to assess the potential impact of chemicals on health and safety fi The chemical industry is technology driven - - new technologies yield new products, new applications, and new benefits to society fi Advancements in toxicology, epidemiology & risk assessment are critical to the chemical industry because they provide an improved scientific foundation for more certainty in decision making that protects workers, consumers & the environment 3 Evolution of Toxicology Evolution of Toxicology Evolution of Toxicology Evolution of Toxicology Empirical Empirical Empirical Empirical dose dose dose dose-related chemical effects related chemical effects related chemical effects related chemical effects Predictive Predictive Predictive Predictive reliable prediction of human toxicity reliable prediction of human toxicity reliable prediction of human toxicity reliable prediction of human toxicity Understanding Mechanisms Understanding Mechanisms Understanding Mechanisms Understanding Mechanisms how chemicals cause effects how chemicals cause effects how chemicals cause effects how chemicals cause effects dose dependency dose dependency dose dependency dose dependency cross species extrapolation cross species extrapolation cross species extrapolation cross species extrapolation Understanding Disease Understanding Disease Understanding Disease Understanding Disease relationship between exposure relationship between exposure relationship between exposure relationship between exposure (magnitude, frequency, duration), dose, (magnitude, frequency, duration), dose, (magnitude, frequency, duration), dose, (magnitude, frequency, duration), dose, toxicant mechanisms,host factors & disease toxicant mechanisms,host f ...
